one. Pharmaceutical Intermediates
Bortezomib Acid Impurity: This is an impurity related to bortezomib, a proteasome inhibitor Utilized in the procedure of a number of myeloma. Its synthesis or study is vital for guaranteeing the purity and protection from the drug.
Abiraterone Acetate Intermediate (CAS NO. 122111-01-seven): A precursor in the synthesis of abiraterone acetate, a drug used in the remedy of prostate most cancers by inhibiting androgen output.
Imatinib Intermediate (CAS NO. 152460-ten-1): A crucial compound while in the synthesis of imatinib, a drug that targets unique varieties of cancer, which includes Long-term myelogenous leukemia (CML).
Docetaxel Intermediate: A compound Employed in the synthesis of docetaxel, a chemotherapy medication that treats various cancers like breast, lung, and prostate cancer.
2. Chemical Impurities and Byproducts
GeMcitabine Intermediates (T6, T9, 8): They're intermediates while in the synthesis of gemcitabine, an anti-most cancers drug. Their examine is crucial for optimizing the production process and ensuring high purity.
Lapatinib Intermediate (CAS NO. 231278-84-five): Lapatinib is made use of to take care of breast most cancers, and these intermediates are involved with its output.
Fulvestrant Intermediates: Fulvestrant is definitely an estrogen receptor antagonist used in the therapy of breast most cancers. Many intermediates assist in the synthesis of this drug.
Paclitaxel Side Chain Acid (CAS NO. 949023-sixteen-9): This intermediate is used in the synthesis of paclitaxel, a chemotherapy drug effective in managing cancers 5R)-3-Benzoyl-2-(4-methoxyphenyl)-4-phenyl-5-oxazolidinecarboxylic acid for example ovarian, breast, and lung cancer.
three. Other Notable Compounds
Irinotecan Hydrochloride Trihydrate (CAS NO. 136572-09-three): A chemotherapy drug Employed in the cure of colorectal cancer and modest mobile lung cancer.
three-Amino-one-hydroxyadamantane (CAS 702-82-nine): This compound is associated with the synthesis of adamantane derivatives, which have many apps, which includes antiviral properties.
Vildagliptin Intermediates: Employed in the production of vildagliptin, an oral drug for style 2 diabetic issues that inhibits the enzyme DPP-4 to control blood sugar stages.
4. Miscellaneous Compounds
D-Gluconic Acid δ-Lactone (CAS NO. 61259-48-one): This compound is linked to the synthesis of various gluconic acid derivatives, that are used in food, pharmaceutical, and industrial applications.
Canagliflozin Intermediate two: A precursor during the synthesis of canagliflozin, a medication made use of to control variety 2 diabetic issues 2'-Difluoro-2'-deoxycytidine-3' by inhibiting sodium-glucose co-transporter two (SGLT2).